Omicron much less prone to trigger hospitalization, UK authorities examine says

Christmas shoppers in London on December 23, 2021.

Hasan Esen | Agency Anadolu | Getty Images

LONDON – According to a UK government study published Thursday, people with the Omicron-Covid variant are far less likely to be hospitalized than the previous Delta strain.

The UK Health Safety Authority said It is estimated that people with Omicron are between 31% and 45% less likely to go to emergency rooms and 50-70% less likely to be hospitalized compared to those with Delta.

The analysis is “preliminary and highly uncertain” due to the small number of Omicron cases currently in hospital, the inability to effectively measure all previous infections, and the limited spread of the new variant to older age groups, the UKHSA said .

The results are based on 132 people admitted to or relocated to emergency rooms. Of these, 17 people had received their booster vaccinations, 74 were double-vaccinated and 27 were unvaccinated. Eight people had received a single vaccination, the vaccination status of 6 people was unknown.

The study says 14 people, ages 52 to 96, died within 28 days of being diagnosed with Omicron.

“Our latest analysis shows an encouraging early signal that people infected with the Omicron variant may have a relatively lower risk of hospitalization than those infected with other variants,” said Jenny Harries, UKHSA executive director. in a statement.

“It should be noted, however, that these are both early data and additional research to corroborate these results.”

The preliminary data are consistent with similar results by scholars in South Africa and research teams from Imperial College London and the University of Edinburgh.

A study published Tuesday by the South African National Institute for Communicable Diseases found that people infected with Omicron are 80% less likely to be hospitalized than other variants. A 70 percent reduction in the risk of serious illness in those not hospitalized was also seen.

The authors of the study, which was not peer-reviewed, warned that this could be due to increased immunity in the population from previous infection or vaccination. South African health officials also said the data should not be extrapolated to all countries.

In Scotland, researchers found that Omicron was two-thirds less likely to be hospitalized than Delta, and they continued to emphasize that how important it is to get a booster vaccination.

It’s still in its infancy, but preliminary results give hope that the human and economic consequences of the heavily mutated strain will not be as great as initially feared. Omicron has spread like wildfire, which has led to the reintroduction of restrictions in some countries as authorities struggle to contain it.

However, due to the higher transferability of omicron, the risk of overloading the health systems in winter is still quite high, as the high number of infections will likely lead to more hospital stays.

Omicron was first identified in South Africa in November and classified as a “variant of concern” by the World Health Organization. The US now reports an average of more than 160,000 new infections per day, while the UK reported more than 100,000 cases on Thursday for the second day in a row.

Son Seok Gu Talks About His Splendid Sort And Courting Type + The Uncommon Cause His Dad and mom Despatched Him To Examine Overseas

Son Seok Gu had his very first variety appearance in the latest episode of “My little old boy“!

Son Seok Gu made a guest appearance as Special MC in the broadcast of the SBS reality show on November 21. After introducing him to the Panel of Prominent Mothers, Shin Dong Yup pointed out, “It’s been about five years since he made his acting debut, but this is the first time he has appeared on a variety show.”

“I was on a radio show once,” explained Son Seok Gu, “but this is my first appearance on a variety show on television.”

host Seo Jang Hoon then brought up the fact that the actor had studied abroad in Canada during elementary school – and that his parents had decided to send him abroad because he was an unusually shy student.

“When I look back today on how I was then, I am a little amazed myself,” said Son Seok Gu. “Well, I’m not that shy, and when I started working as an adult I got a lot better. But looking back how [shy I was], even I feel like it was almost like a disease. As soon as school was over, I went home straight away, and on the weekends I just stayed home and didn’t go out. Even if my parents took me somewhere, for example to a department store, I couldn’t say a single word until I got home. “

“So my father was very worried about me,” the actor continued. “And at some point I also had the feeling that something had to change too.”

Later, when asked about his real life dating style, Son Seok Gu replied, “When I lived in Canada, I had a girlfriend and it was Valentine’s Day. Saw a photo of this really cool restaurant on an island that needs a boat to go to and I decided to take it there based on that one photo I saw. So we took the boat to the island, but when we got there the island itself was completely shrouded in darkness so we had to take the boat and come right back. It was then that I realized: ‘Dating is not easy.’ “

“After that, in order to prevent such a situation in which I apologized, [my date], I try to plan my appointments in advance, ”said Son Seok Gu. “But I don’t think I’m very good at it.”

As for his ideal type, Son Seok Gu revealed that he wants to date someone who is funny and humorous. When Seo Jang Hoon urged him whether that’s the only thing that matters to him, the actor replied playfully, “It’s one of about 25 things that are important to me. But someone who has fun and a sense of humor is really important to me. “

See Son Seok Gu in “Jirisan”With subtitles here …

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Blood clots linked to AstraZeneca shot have 22% mortality fee: examine

A paramedic prepares doses of the AstraZeneca vaccine for patients at a walk-in COVID-19 clinic at a Buddhist temple in the Smithfield suburb of Sydney on Aug. 4, 2021.

Saeed Khan | AFP | Getty Images

A new study has provided further details on the “rare but devastating” blood clotting complications associated with the Oxford-AstraZeneca Covid-19 vaccine.

In a peer-reviewed article published Wednesday in the New England Journal of Medicine, Massachusetts Medical Society scientists analyzed the first 220 cases of the disease reported in the UK.

The Oxford-AstraZeneca vaccine – now one of the most widely used Covid vaccines in the world – was launched in the UK in January, making it the first country to give the vaccine.

A very small number of people who have been vaccinated with the AstraZeneca Vaccine have suffered blood clots. The condition, described by health authorities marked as “extremely rare” by blood clots accompanied by low platelet counts.

Massachusetts Medical Society study uses data from 294 patients who presented to UK hospitals between March 22nd and June 6th) – have been identified.

All of these patients had received their first dose of the Oxford-AstraZeneca shot and went to hospital with symptoms between 5 and 48 days after their vaccination. The average time between vaccination and hospitalization was 14 days, the results showed.

The overall mortality rate for VITT in the study was 22%.

The researchers also found that 41% of patients who presented with VITT were not diagnosed with any underlying health problems. Of those who reported a past or current illness, the study found that there were no prevalent diseases or medications that were “unexpected in the general population”.

“Against the background of a successful vaccination program in the UK, VITT has emerged as a rare but devastating complication,” the study’s authors said in their report. “We found that it often affects young, otherwise healthy vaccine recipients and is associated with high mortality.”

“In our cohort, 85% of the patients were younger than 60 years, although the (Oxford / AstraZeneca) vaccination was predominant in older adults,” the scientists found.

As a precautionary measure, the UK is offering people under 40 years of age an alternative to the Oxford AstraZeneca vaccine since May.

People diagnosed with VITT were between 18 and 79 years old, with the mean age being 48, the study showed.

As of July 28, inclusive, an estimated 24.8 million first doses of the Oxford-AstraZeneca Covid vaccine had been administered in the UK, with an estimated 23.6 million second doses received.

On July 28, government figures show that for every million first or unknown doses of the Oxford AstraZeneca shot, 14.9 people developed a rare blood clot with low platelet counts. After a second dose of the vaccine, the number dropped to 1.8 cases per million.

The overall death rate for that period was 18%, the government data showed, with 73 deaths. Six of these occurred after the second dose.

Late last month, AstraZeneca published a study that found the VITT rate was 8.1 per million after the first dose of its vaccine, which dropped to 2.3 per million after a second dose.

According to official information, 411 suspected cases of VITT had been reported in Great Britain by July 28.

Benefits vs. Risks

Ann Taylor, AstraZeneca’s chief medical officer, said in March that the prevalence of blood clots in the number of people vaccinated is lower than what would normally be expected in the general population.

Both UK and EU drug regulators have identified possible links between the Oxford AstraZeneca vaccine and rare blood clots.

In April, the company announced it would comply with government requests in the UK and Europe to update its Covid vaccine labels. However, it stressed that WHO had said “a causal relationship is considered plausible but not confirmed”.

The UK Joint Vaccination and Immunization Committee has stated time and time again that for the vast majority of people, the benefits of the Oxford-AstraZeneca vaccine continue to outweigh the risks.

Several health authorities including the WHO, the European Medicines Agency and the International Society for Thrombosis and Hemostasis agree that the benefits of giving the vaccine outweigh the risks.

New Covid research hints at long-term lack of mind tissue, Dr. Scott Gottlieb warns

Dr. Scott Gottlieb warned on Thursday of the potential for long-term brain loss related to Covid, citing new study from the UK.

“In short, the study suggests that there could be long-term loss of brain tissue from Covid, and that would have some long-term consequences,” said the former FDA chief and CNBC employee.

“You could compensate for that over time, so the symptoms of it may go away, but you will never regain the tissue if it is actually destroyed by the virus,” said Gottlieb, who is the board member of the Covid vaccine manufacturer Pfizer.

The UK study looked at brain imaging before and after coronavirus infection, specifically looking at the potential effects on the nervous system.

Gottlieb explained it to CNBC’s “The News with Shepard Smith” that the destruction of brain tissue could explain why Covid patients have lost their sense of smell.

“The decrease in the amount of cortical tissue happened by chance in regions of the brain that are near the places responsible for the odor,” he said. “What it suggests is that the odor, the loss of smell, is just an effect of a more primary process that is going on, and that process is actually the shrinking of the cortical tissue.”

Disclosure: Scott Gottlieb is a CNBC employee and a member of the board of directors of Pfizer, genetic testing startup Tempus, health technology company Aetion Inc., and biotechnology company Illumina.

The place are unvaccinated Individuals touring? Huge cities, research suggests

Vaccinated and unvaccinated Americans have different attitudes about traveling this spring, according to a marketing tech company. And they don’t differ in the way you might assume.

With Travel bookings are increasingData from New York’s Zeta Global shows that unvaccinated Americans seem more comfortable traveling – and to more populated places – than vaccinated people.

Vaccinated people wait longer to travel

Zeta Global conducted a survey of 3,700 US consumers in mid-March and combined the results with information on hotel and airport visits by respondents in February and March.

In the survey, 67% of vaccinated respondents said they won’t travel until the end of May, but only 59% of non-vaccinated Americans said they would wait that long.

Vaccinated care more about health measures

More than 80% of vaccinated people who responded to the survey said they were concerned about public health restrictions at intended destinations, compared with just 38% of unvaccinated travelers who shared this concern.

It is possible that vaccinated people will be more comfortable traveling when there are health restrictions, while non-vaccinated travelers will be more interested in how local restrictions limit their travel, said David Steinberg, CEO of Zeta Global.

The survey found that 62% of unvaccinated travelers were “not at all” concerned with public health restrictions in their travel destinations, while only 19% of vaccinated travelers said so.

Travel to different places

Zeta Global data showed that the top travel destinations for February and March as a whole were New York City, Denver, Atlanta, Dallas-Fort Worth, Philadelphia, and two cities in Florida – Orlando and Tampa.

However, the trends diverged when broken down by travelers’ vaccination status, said Neej Gore, the company’s chief data officer.

Top travel destinations for vaccinated travelers

  • Minneapolis-St. Paul
  • Columbus, Ohio
  • Washington, DC
  • Boston
  • Baltimore
  • Cincinnati
  • Indianapolis

Source: Zeta Global, hotel and flight visit

“Vaccinated Americans choose locations in the Northeast and Midwest,” Gore told CNBC, adding that the unimmunized had traveled to locations in the south and locations along the west coast.

Top travel destinations for unvaccinated travelers

  • Houston
  • Miami-Fort Lauderdale
  • The angel
  • Salt Lake City
  • San Antonio
  • Seattle-Tacoma
  • Austin, Texas
  • Little Rock, Ark.

Source: Zeta Global, hotel and flight visit

However, April travel data showed a shift in travel habits. Unvaccinated people went to densely populated cities, while the unvaccinated went to vast areas according to travel dates compiled by Zeta.

“Las Vegas is the city with the greatest relative change,” said Gore, citing data showing that the number of unvaccinated travelers visiting Las Vegas hotels tripled in April from the previous month during the month The number of vaccinated visitors there has declined.

Similarly, the number of unvaccinated travelers going to Florida in April increased (+ 6%) but declined (-16%) among vaccinated travelers.

Unofficially known as “Big Sky Country,” Montana attracted more vaccinated than unvaccinated Americans last month.

Mike Kemp | In Pictures Ltd. | Corbis historical | Getty Images

The trends in Florida are primarily due to in-depth travel to Miami and Fort Lauderdale, Zeta Global said. Trips there increased by 77% for unvaccinated travelers and 33% for vaccinated travelers.

While the Northeast and Midwest continue to be popular destinations for vaccinated travelers, “more vaccinated respondents are currently traveling to the Northwest,” said Gore, based on data showing an increase in vaccinated travelers to Oregon, Washington, Montana and Dakotas.

Travel to these states did not increase among unvaccinated people, with the exception of Oregon, which, according to the company, is mainly due to increased travel by both groups to Portland.

Northeast Europeans fly less

Adobe Digital Economy Index 2021, released last month, showed regional differences in summer travel habits. The report showed that Northeast Europeans fly less than other Americans. The flight bookings in March come from the region and only account for 56% of the prepandemic levels. This number does not match the booking setbacks from the West (63%) and the South (70%) and the Midwest (75%).

Adobe’s research shows that Northeasterners’ flight purchases are more closely related to regional vaccination rates. For every 1% increase in vaccinations in the Northwest, there was a 3.2% increase in flight bookings, the highest of any region in the United States.

It is those who are not vaccinated who should be afraid of traveling.

Harry Severance

Duke University School of Medicine

“The northeast was badly hit in the early days of the pandemic, which likely caused residents to restrict themselves when it came to travel and social interactions,” said Taylor Schreiner, director of Adobe Digital Insights.

However, the area is densely populated, said Schreiner, so that “viable alternatives for seeing family and friends” exist.

“A large part of the US population is accessible to New York by car,” he said.

“Increased risk” for those not vaccinated

Harry Severance, an associate professor at Duke University School of Medicine, said people who were vaccinated early are more likely to be concerned about contracting Covid-19 and have a better knowledge of the acute and chronic effects of the disease.

“So I suspect that this group will continue to have significant concerns about contracting the disease after vaccination,” he said.

Severance said the thought process is changing as evidence shows people who have been vaccinated are “less susceptible” to Covid-19 infections, and when they do get sick, infections are typically mild with a “significantly reduced ability to spread the disease.” “.

“It is those who are not vaccinated who should be afraid to travel,” he said.

“Those who are not vaccinated are at increased risk when they congregate in large groups of likewise unvaccinated people,” Severance said, “especially when these groups congregate from across the country as the risk increases, various Being exposed to Covid variants. ” . “

Oxford to launch human problem trial to check immune response

Caroline Nicolls will receive an injection of the Moderna Covid-19 vaccine administered by Nurse Amy Nash at Madejski Stadium in Reading, west of London, on April 13, 2021.

STEVE PARSONS | AFP | Getty Images

LONDON – Oxford University researchers announced the start of a Human Challenge study on Monday to better understand what happens when people who have already contracted the coronavirus become infected for the second time.

The researchers will investigate what kind of immune response can prevent people from becoming infected with Covid-19 again and examine how the immune system reacts to the virus a second time.

Little is currently known about what happens to people who had the virus the second time they were infected.

The experiment is carried out in two phases with different participants in each phase. The first phase is slated to begin this month and the second phase is slated to begin in summer.

In medical research, Human Challenge studies are controlled studies in which participants are intentionally exposed to a pathogen or beetle to study the effects.

“Challenge studies tell us things that other studies cannot because, unlike natural infections, they are tightly controlled,” said Helen McShane, chief investigator for the study and professor of vaccinology in the Department of Pediatrics at Oxford University.

“If we re-infect these participants, we will know exactly how their immune systems responded to the first COVID infection, when exactly the second infection occurs, and how much virus they have,” said McShane.

It is hoped that the study will help improve scientists’ basic understanding of the virus and develop tests that can reliably predict whether people will be protected.

What happens in each phase?

In the first phase, up to 64 volunteers between the ages of 18 and 30 who were previously infected naturally will be re-exposed to the virus under controlled conditions.

Researchers will oversee attendees’ care while they perform CT scans of the lungs and MRI scans of the heart while isolating in a specially designed suite for at least 17 days.

All participants must be fit, healthy and have fully recovered from their initial infection with Covid to minimize the risk.

Study participants will only be released from the quarantine unit if they are no longer infected and there is a risk of the disease spreading.

A view of the City of London on a clear day.

Vuk Valcic | SOPA pictures | LightRocket via Getty Images

In the second phase of the experiment, two different areas are examined.

“First we will very carefully define the basic immune response of the volunteers before we infect them. We will then infect them with the dose of virus selected from the first study and measure how much virus we can detect after infection. We will then.” to be able to understand what kind of immune responses protect against re-infection, “said McShane.

“Second, we will measure the immune response several times after infection so we can understand what immune response is being generated by the virus,” she added.

The entire study period is 12 months, including at least eight follow-up appointments after discharge.

“This study has the potential to change our understanding by providing high-quality data on how our immune systems react to a second infection with this virus,” said Shobana Balasingam, senior research advisor on vaccines at Wellcome, a nonprofit that funded the study.

“The results could have important implications for the future management of COVID-19, influencing not only vaccine development but research into the range of effective treatments that are also badly needed,” Balasingam said.

Covid variant from South Africa was capable of ‘break via’ Pfizer vaccine in Israeli examine

An Israeli health worker from Maccabi Healthcare Services prepares to deliver a dose of the Pfizer BioNtech vaccine in Tel Aviv on February 24, 2021.

Jack Guez | AFP | Getty Images

The coronavirus variant, first discovered in South Africa, can be part of the protection of the Pfizer– –BioNTech Vaccine, according to a new Israeli studythat has not yet been reviewed by experts.

Researchers from Tel Aviv University and Clalit, the largest health organization in Israel, examined nearly 400 people who had tested positive for Covid-19 after receiving at least one dose of the vaccine. They compared it to the same number of people who were infected and not vaccinated.

The researchers found that the prevalence of the South African variant known as B.1.351 was about eight times higher in patients who received two doses of the vaccine than in those who were not vaccinated. The data, released online over the weekend, suggest that B.1.351 may “break through” the vaccine’s protection better than the original strain, the researchers in the study wrote.

“Based on the patterns in the general population, we would have expected only one case of the South African variant, but we saw eight,” said Professor Adi Stern, who led the research. told the times of Israel. “We can say it’s less effective, but more research is needed to see exactly how much.”

CNBC asked Pfizer to comment on the study.

The new data comes as public health officials are increasingly concerned that highly contagious variants, studies have shown can reduce the effectiveness of vaccines, could slow global advances in the pandemic.

Last month, CDC Director Dr. Rochelle Walensky issued a terrible warning, telling reporters that she feared the United States was facing “impending doom” as variants spread and daily Covid-19 cases rise again, threatening to move more people to the US send hospital.

“I’m going to pause here, I’m going to lose the script, and I’ll be thinking about the recurring feeling I have of impending doom.” she said March 29th. “We can look forward to so much, so much promise and potential where we are and so much reason to hope, but right now I’m scared.”

Israel launched its national vaccination campaign in December, prioritizing people aged 60 and over, healthcare workers, and people with comorbid illnesses. By February, it was the world leader in vaccinations, vaccinating millions of its citizens against the virus.

In January, Pfizer and the Israeli Ministry of Health signed a collaboration agreement to monitor the real effects of its vaccine.

The researchers found that the study’s main limitation was sample size. B.1,351 only made up about 1% of all Covid-19 cases, they said. B.1.1.7, the variant first identified in Great Britain, is more common.

As the variants spread, drug manufacturers tested whether a third dose would offer more protection.

In February, Pfizer and BioNTech said tThey tested a third Dose of their Covid-19 vaccine to better understand the immune response to new variants of the virus.

Examine: Tween TV viewers get new message about worth of fame | Leisure

Adolescents approaching puberty are also particularly vulnerable to media influences, as they “dream of their future by shaping their value systems,” the study says. The researchers used Nielsen ratings to determine the leading tween shows and then asked study participants about the values ​​of the TV characters.

Viewers perceived different messages depending on whether they were watching a reality series or a script series. The previous study, published in 2011, was done on the verge of the reality TV boom and only included scripts.

The new study found that the comedies “Girl Meets World” and “The Thundermans” appeared to be shifting away from the emphasis on fame, but the competitive series “American Ninja Warrior” and “America’s Got Talent” continued to reflect this trend “Self-Focused Values” from 2007.

“When tweens watch, admire and identify with people who care about fame and gain most, those values ​​can become even more important in our culture,” the report’s lead author Agnes Varghese said in a statement.

In previous years, the study found that community spirit, benevolence and tradition were emphasized in hit series like “The Andy Griffith Show” from 1967. “Happy Days”, 1977; “Growing Pains” (1987) and “Sabrina the Teenage Witch” (1997).

The community ranked first three of those years, dropping once to number 2. Then the fame that remained at the bottom of the list soared to first place in 2007, with researchers shifting to the adoption of social media platforms like Facebook and returned Youtube.

Research: Lack of variety in Hollywood prices trade $10B | Leisure

NEW YORK (AP) – For years, researchers have said a lack of diversity in Hollywood movies not only reflects poorly on demographics, but is bad business too. A new study by the consulting firm McKinsey & Company estimates how much Hollywood is still on the table: 10 billion US dollars.

The McKinsey report released on Thursday analyzes how inequality shapes the industry and how much it ultimately costs its bottom line. The consultancy concluded the $ 148 billion film and television industry is losing $ 10 billion, or 7 percent, each year by undervaluing black films, filmmakers, and executives.

“Fewer black-led stories are told, and when they do, these projects have consistently been underfunded and undervalued, even though they often achieved higher relative returns than other properties,” the study authors wrote: Jonathan Dunn, Sheldon Lyn, Nony Onyeador and Ammanuel Zegeye.

The study, which spans 2015-2019, was conducted over the past six months and was based on previous research from the University of California, Los Angeles, the University of Southern California, and von Nielsen. The BlackLight Collective, a coalition of black leaders and talent in the industry, works with McKinsey researchers. The company also anonymously interviewed more than 50 executives, producers, agents, actors, directors and writers.

McKinsey attributed at least part of Hollywood’s slow progress to its complex and multi-layered business – an ecosystem of production companies, networks, distributors, talent agencies, and other separate but intertwined areas.

However, the lack of black representation in top positions of power plays a prominent role. The study found that 92% of movie managers are white and 87% are on television. About 90% of the agents and executives of the three largest talent agencies are white – and 97% are partners.

The researchers found that films with a black or co-lead are budgeted 24% less than films that don’t – an inequality that almost doubles when two or more blacks direct, produce, or write.

McKinsey recommends, among other things, the creation of a “well-funded third-party organization” for a more comprehensive approach to racial equality. The film business is less diverse than industries such as energy, finance and transport.

Following protests against Black Lives Matter last year, McKinsey announced that it would allocate $ 200 million to volunteer work promoting racial equality.

Grammys to associate with Berklee, ASU for research on girls | Leisure

NEW YORK (AP) – The Recording Academy is partnering with Berklee College of Music and Arizona State University to complete a study of women’s representation in the music industry.

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